Publications

Beaver AK, Keneskhanova Z, Cosentino RO, Weiss BL, Awuoche EO, Smallenberger GM, Buenconsejo GY, Crilly NP, Smith JE, Hakim JMC, Zhang B, Bobb B, Rijo-Ferreira F, Figueiredo LM, Aksoy S, Siegel TN, Mugnier MR*. Tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei. Nature. 2024 Oct 30. doi: 10.1038/s41586-024-08151-z.

Hakim JMC, Guarnizo SAG, Machaca EM, Gilman RH, Mugnier MR*. Whole Genome Assembly of a Hybrid Trypanosoma cruzi Strain Assembled with Nanopore Sequencing Alone. G3. 2024 Jun 5;14(6):jkae076. doi: 10.1093/g3journal/jkae076.

Crilly N, Zita MD, Beaver A, Sysa-Shah P, Bhalodia A, Gabrielson K, Adamo L*, Mugnier MR*. A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction. bioRxiv. 2023 Oct 21;. doi: 10.1101/2023.10.05.560950.

Duque C, So J, Castro-Sesquen YE, DeToy K, Gutierrez Guarnizo SA, Jahanbakhsh F, Machaca EM, Miranda-Schaeubinger M, Chakravarti I, Cooper V, Schmidt ME, Adamo L, Marcus R, Talaat KR, Gilman RH, Mugnier MR*. Immunologic changes are detectable in the peripheral blood transcriptome of clinically asymptomatic Chagas cardiomyopathy patients. bioRxiv. 2023 Oct 5;. doi: 10.1101/2023.10.03.560680.

Hakim JMC, Waltmann A, Tinajeros F, Kharabora O, Machaca EM, Calderon M, Del Carmen Menduiña M, Wang J, Rueda D, Zimic M, Verástegui M, Juliano JJ, Gilman RH, Mugnier MR*, Bowman NM*. Amplicon Sequencing Reveals Complex Infection in Infants Congenitally Infected With Trypanosoma Cruzi and Informs the Dynamics of Parasite Transmission. J Infect Dis. 2023 Sep 15;228(6):769-776. doi: 10.1093/infdis/jiad125.

So J, Sudlow S, Sayeed A, Grudda T, Deborggraeve S, Mumba Ngoyi D, Kashiama Desamber D, Wickstead B, Lejon V, Mugnier MR*. VSGs Expressed during Natural T. b. gambiense Infection Exhibit Extensive Sequence Divergence and a Subspecies-Specific Bias towards Type B N-Terminal Domains. mBio. 2022 Dec 20;13(6):e0255322. doi: 10.1128/mbio.02553-22.

Crilly NP and Mugnier MR*. Thinking outside the blood: Perspectives on tissue-resident Trypanosoma brucei. PLOS Pathogens. 2021 Sep 16;17(9):e1009866.

Romero-Meza G, Mugnier MR*. Trypanosoma brucei. Trends in Parasitolology. 2020 Jun;36(6):571-572. doi: 10.1016/j.pt.2019.10.007. PubMed PMID: 31757771; PubMed Central PMCID: PMC7375462.

McWilliam KR, Ivens A, Morrison LJ, Mugnier MR*, Matthews KR*. Developmental competence and antigen switch frequency can be uncoupled in Trypanosoma brucei. PNAS. 2019 Nov 5;116(45):22774-22782. doi: 10.1073/pnas.1912711116. PubMed PMID: 31636179; PubMed Central PMCID: PMC6842576.

McCulloch R, Cobbold CA, Figueiredo L, Jackson A, Morrison LJ, Mugnier MR, Papavasiliou N, Schnaufer A, Matthews K. Emerging challenges in understanding trypanosome antigenic variation. Emerging Topics in Life Sciences. 2017 Dec 22;1(6):585-592. doi: 10.1042/ETLS20170104. PubMed PMID: 30271884; PubMed Central PMCID: PMC6162063.

Danae Schulz, Monica R. Mugnier, Catherine E. Boothroyd, and F. Nina Papavasiliou. (2016) Detection of Trypanosoma brucei Variant Surface Glycoprotein Switching by Magnetic Activated Cell Sorting and Flow Cytometry. Journal of Visualized Experiments. Oct 19;(116). 

Monica R. Mugnier, C. Erec Stebbins, and F. Nina Papavasiliou. (2016) Masters of Disguise: Antigenic variation and the VSG coat in Trypanosoma brucei. PLOS Pathogens. 12(9): e1005784. 

Monica R. Mugnier, F. Nina Papavasiliou, and Danae Schulz. (2016) Vesicles as Vehicles for Virulence. Trends in Parasitology. 32(6):435-6.

Galadriel Hovel-Miner, Monica R. Mugnier, Benjamin Goldwater, F. Nina Papavasiliou. (2016) A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive. PLOS Genetics. 12:e1005994.

Danae Schulz, Monica R. Mugnier, Eda-Margaret Paulsen, Hee-Sook Kim, Chun-wa W. Chung, David F. Tough, Inmaculada Rioja, Rab K. Prinjha, F. Nina Papavasiliou and Erik W. Debler. (2016) Bromodomain proteins contribute to maintenance of bloodstream form stage identity in the African trypanosome. PLOS Biology. 13: e1002316.

Monica R. Mugnier, George A. M. Cross, F. Nina Papavasiliou. (2015) The in vivo dynamics of antigenic variation in Trypanosoma brucei. Science. 347(6229):1470-1473.

Galadriel A. Hovel-Miner, Monica R. Mugnier, F. Nina Papavasiliou, Jason Pinger, Danae Schulz. (2015) A Host-Pathogen Interaction Reduced to First Principles: Antigenic Variation in T. brucei. Results and Problems in Cell Differentiation. 57:23-46.

Galadriel A. Hovel-Miner, Catharine E. Boothroyd, Monica Mugnier, Oliver Dreesen, George A.M. Cross, F. Nina Papavasiliou. (2012) Telomere Length Affects the Frequency and Mechanism of Trypanosoma brucei Antigenic Variation. PLOS Pathogens. 8:e1002900.